Aggression/agitation

These medications are prescribed for aggression. The medications in bold font are the FDA-approved medications for aggression/agitation. These medications can be prescribed (by mouth - PO) to manage aggression/agitation.

Off-label prescriptions for aggression.

  • clozapine
  • propranolol
  • zuclopenthixol
  • quetiapine
  • chlorpromazine
  • Loxapine
  • guanFACINE (child/adolescents)

When a provider (MD, DO, NP, or PA) prescribes a prescription that the U.S. Food and Drug Administration (FDA) has not approved to treat a disorder, this is known as an off-label prescription. This is a frequent and legal practice. Today, one out of every five prescriptions is for off-label use.

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